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Biotransformation terrestrial mammals

Meanwhile, in laboratory studies the metabolism of PCBs and DDE was also confirmed by detection of their metabolites.63 Based on the many laboratory studies with terrestrial mammals (rodents mainly) and the work mentioned above, it is now believed that biotransformation occurs in three phases ... [Pg.101]

As with polar bears, wolverines and Arctic foxes also appear to have sizable capacity for biotransforming POPs, as evidenced by enantiomer analysis. Wolverines captured from Iceland and the Canadian Arctic had enrichments of (—)-PCBs 136 and 149 in livers, with mean EFs of 0.41 and 0.46, respectively [268]. While these enrichments were similar to those of a-HCH (mean EF of 0.42) and heptachlor epoxide (mean EF of 0.55), they were not as stereoselective as those of /ra 5-chlordane (mean EF of 0.65) and oxychlordane (mean EF of 0.71) [268]. Populations of Arctic foxes in Iceland feeding mostly on marine mammals had much higher POP concentrations in liver tissue than those with a terrestrial diet, but had similar enrichments of (-l-)-chlordane [267]. As with wolverines, Arctic fox livers [268] had modest enrichments of (—)-a-HCH, (+)-PCBs 136 and 149, and El -PCB 95 on Chirasil-Dex, with mean EFs of 0.41, 0.48, 0.54, and 0.55 respectively. These enrichments were again minor compared to that of the OC compounds, which had mean EFs of 0.61 for cw-chlordane, 0.89 for /ra 5-chlordane, 0.68 for oxychlordane, and 0.73 for heptachlor epoxide. Depletions of labile analytes compared to recalcitrant compounds... [Pg.105]


See other pages where Biotransformation terrestrial mammals is mentioned: [Pg.78]    [Pg.93]    [Pg.103]    [Pg.315]    [Pg.181]    [Pg.209]    [Pg.47]    [Pg.82]   


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Mammals

Terrestrial

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