Biotechnology research efforts

We have chosen carotenoid biosynthesis as the example system for demonstrating the prospects of biotechnology of food colorants for several reasons. Carotenoid biosynthesis is the second most understood system. Multiple examples of valuable food colorant engineering in fungi, bacteria, and plants have been reported. Finally, carotenogenesis in cereal crops such as maize and rice is the primary focus of our research efforts. Hopefully, we provide the food technologist with a template with which to examine other industrially important pigment systems. 

The Role of the Virginia Biotechnology Research Park in Our Drug Discovery Efforts... 

The interaction between reactor miniaturization and catalyst nanotailoring to achieve an effective PI has been emphasized by Charpentier [28] and Dautzen-berg [29]. The role of membranes in PI has been discussed by Drioli ef al. [30]. This short overview of the recent state-of-the-art, although limited to reviews published in the last few years, evidences the intense research effort and broad-range type of applications for PI, from refinery and petrochemistry to biotechnology, fine and specialty chemical production. 

After a pharmaceutical or biotechnology company, commonly referred to as the sponsor, has decided to use CROs to support some or all of the nonclinical research effort in a drug development program, management or the project team responsible for the development of the drug candidate assigns individuals to identify and select the appropriate CROs. The steps in a selection process should include, but are not be limited to ... 

What are the biotechnology efforts in the ARS and where are they located the profiles of our scientists as related to industry and university colleagues and an overview of research efforts they are pursuing will be covered in this chapter. 

It is clear that biotechnology research will become increasingly significant in global efforts to improve agricultural production and protect the environment. 

The therapeutic and economic importance of the alkaloids vinblastine (36) and vincristine (37) has stimulated a major research effort on the plant cell biotechnology of Catharanthus roseus. This work, which has recently been extensively reviewed (592), has resulted in several patents (Table XXIX). Concomitantly, modern analytical procedures, for example, HPLC 635,637), GC-MS 636), immunoassays 638-641), and supercritical fluid chromatography/mass spectrometry 642), have been developed to high sensitivity and selectivity to study alkaloid formation in plant tissues. 

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