Biotechnology polyketides

Baltz, R.H. (2006) Molecular engineering approaches to peptide, polyketide and other antibiotics. Nature Biotechnology, 24, 1533. 

Kittendorf, J.D. and Sherman, D.H. (2006) Developing tools for engineering hybrid polyketide synthetic pathways. Current Opinion in Biotechnology, 17, 597. 

Del Vecchio, F., Petkovic, H., Kendrew, S.G. et al. (2003) Active-site residue, domain and module swaps in modular polyketide synthases. Journal of Industrial Microbiology Biotechnology, 30, 489. 

Khosla, C.Z.R. (1996) Generation of polyketide libraries via combinatorial biosynthesis. Trends in Biotechnology, 14, 335-341. 

Menzella, H.G., Reid, R., Carney, J.R. et al. (2005) Combinatorial polyketide biosynthesis by de novo design and rearrangement of modular polyketide synthase genes. Nature Biotechnology, 23, 1171-1176. 

Ward, S.L., Desai, R.P., Hu, Z. et al. (2007) Precursor-directed biosynthesis of 6-deoxyerythronolide B analogues is improved by removal of the initial catalytic sites of the polyketide synthase. Journal of Industrial Microbiology and Biotechnology, 34, 9-15. 

Leadlay, P.F., Staunton, J., Oliynyk, M. et al. (2001) Engineering of complex polyketide biosynthesis — insights from sequencing of the monensin biosynthetic gene cluster. Journal of Industrial Microbiology Biotechnology, 27 (6), 360-367. 

Stocker-Worgotter E (2005) Approaches to a biotechnology of lichen forming fungi induction of polyketide pathways and the formation of chemosyndromes in axenically cultured mycobionts. Recent Res Dev Phytochem 9 115-131... 

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