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Biotechnology pharmaceuticals adverse effects

The important differences between biotechnology products and conventional pharmaceuticals mean that the imthinking or routine application of standard safety tests could result in the release of biotechnologically-derived pharmaceuticals for clinical trials without adequate warning of possible adverse effects in humans. [Pg.51]

Typical adverse effects related to biotechnologically-derived pharmaceuticals are not due simply to impurities or accidental overdose, but can theoretically be associated with the molecular background of the receptor, such as pleiotropisms, redundancies, receptor sub-unit function and possible unexpected amplification of receptor signalling. Several examples of receptor-mediated toxicity with biotech products are shown in Table 6.1 (Inoue, 1996). [Pg.54]

See other pages where Biotechnology pharmaceuticals adverse effects is mentioned: [Pg.92]    [Pg.39]    [Pg.546]    [Pg.333]    [Pg.117]    [Pg.598]    [Pg.223]    [Pg.3]    [Pg.147]    [Pg.53]    [Pg.179]    [Pg.179]    [Pg.165]    [Pg.81]    [Pg.734]    [Pg.990]    [Pg.130]    [Pg.222]    [Pg.1257]    [Pg.189]    [Pg.1653]   
See also in sourсe #XX -- [ Pg.137 ]



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