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The Biotechnology Era Between

The modern blockbuster products era started four decades ago with Valium (Roche, diazepam), which was the most prescribed global medicine between 1969 and 1982 with 2.3 billion doses taken in 1978 and the first medicine to achieve peak sales of 200 million. It was later joined by benzodiazapine, antibiotics, and non-stroidal analgesics and by several innovative medicines like Captopril, Capoten, and Mevacor in the 1980-1990 period [9-13]. The period of billion-dollar pharmaceutical brands started 10 years ago and of biotechnology brands about 5 years ago. A commercial report estimated the total blockbuster medicine sales in 2005 at 145 billion and forecasted strong growth in biologies [14]. [Pg.162]

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