Biosynthetic pathways daidzein

The precursors of flavonoid biosynthesis include shikimic acid, phenylalanine, cinnamic acid, and p-coumaric acid. Shikimic acid acts as an intermediate in the biosynthesis of aromatic acid. The basic pathways to the core isoflavonoid skeletons have been established both enzymatically and genetically [16]. The synthesis of isoflavones can be broadly divided into three main synthetic pathways the formylation of deoxybenzoins, the oxidative rearrangement of chalcones and flavanones, and the arylation of a preformed chromanone ring. In leguminous plants, the major isoflavonoids are produced via two branches of the isoflavonoid biosynthetic pathway, and the different branches share a majority of common reactions [1]. Unlike the common flavonoid compotmds, which have a 2-phenyl-benzopyrone core structure, isoflavones, such as daidzein and genistein, are 3-phenyl-benzopyrone compounds. Biochemically, the synthesis of isoflavones is an offshoot of the flavonoids biosynthesis pathway. Several attempts have aimed to increase... 

Biosynthesis of HydroxyphaseoUin.—The biosynthesis of a newly discovered pterocarpan (48)" has been investigated in disease-resistant soya bean hypo-cotyls. [U- C]Phenylalanine and [9- C]isoliquiritigenin were readily incorporated into (48). Label also appeared in daidzein, coumestrol, and spjagol (49). The biosynthetic pathway followed the generally expected route... 

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