Biosynthetic combinatorial libraries system

Combinatorial approaches in synthetic chemistry allow the high-throughput screening of millions of compounds. It is the aim to establish such approaches in biosynthetic systems by creating module assemblies, which provide a new tool to create peptide libraries. The large number of different modules in peptide synthetase systems is suitable for creating a pool of many different enzymes in order to detect a useful compound in the near future [2,51],... 

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