Biomolecular rate constants for

Anbar, M. and Neta, P. (1967). A compilation of specific biomolecular rate constants for the reaction of hydrated electrons, hydrogen atoms and hydroxyl radicals with inorganic and organic compounds in aqueous solutions. Int. J. Appl. Radiat. Isot. 18, 493-497. 

Table 2.4 Approximate Expressions and Values for Biomolecular Rate Constants for Different Types of Reactants and Complexes...

A detailed electrokinetic analysis of osmium mediator/laccase biocathodes was published in 2008 by GaUaway and Calabrese Barton [31]. In their work, the authors described the biomolecular rate constants for mediation to be between 250 and 9.4 X10" s when the redox potentials of mediator and laccase are close or far... 

To treat more realistic models for the kinetics of biomolecular encounters, a simulation approach has been developed and applied to proteins.370,371,3718 This approach merges stochastic dynamics methodology (Chapt. IV.D) with the analytic result for the Debye rate constant for a pair of particles, moving diffusively through solvent with a centrosymmetric interaction potential.365 The analytical expression for the Debye rate constant, ko(,R), to first achieve a separation, R, is given by... 

Table II. Affinity Equilibrium (K ), Phopshorylation Rate (1 2) and Biomolecular Rate (Ic,) Constants for the Inhibition of AChE by ANTX-A(S) and DFP...

The reaction scheme in Fig. 26 gives a detailed picture of the main reactions initiated by the excitation of the dye molecule at the surface of an organic crystal. The rate constants connecting the reactants with the products are given in the dimensions s 1 for monomolecular reactions and in the dimensions cm3 s 1 for biomolecular reactions. Going from left to right in the first line a J describes the... 

The biomolecular inhibition rate constant (ifj) describes both the affinity and the rate of cholinesterase phosphorylation and is an indicator of inhibitory potency (Kousba et al 2004 Kardos and Sultatos, 2000 Amitai et al., 1998 Carr and Chambers, 1996). A typical determination is illustrated in Fig. 10 for the in vitro inhibition of rat BuChE with chlorpyrifos-oxon. In this example, the Kj was determined by incubating BuChE with varying concentrations of ehloropyrifos-oxon (0.25-5 nAf) the maximum inhibition ranged from 10 to 90% during a 7- to 30-min incubation period (Kousba et al., 2003). The slopes obtained from this analy.sis were then analyzed by linear regression to calculate a K (Fig. lOB). Similar in vitro approaches have been used to calculate the spontaneous first-order reactivation... 

Disregarding the tunnel effects (see Sect. 1.5) and staying within the approximation rigid rotator-harmonic oscillator, one may, for the biomolecular reaction A -h B), calculate the kinetic isotopic effect (ratio between the reaction rate constant of the compound with the light isotope and the rate constant K2 of the compound containing the heavy isotope) from the Bigeleisen equation ... 

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