Biomedical applications drug delivery

R. Esfand and D. A. Tomalia, Poly(amidoamine) (PAMAM) dendrimers From biomimicry to drug delivery and biomedical applications, Drug Discov. Today, 6 (2001) 427 136. 

Shek, P.N., Ed. Liposomes in Biomedical Applications Drug Targeting and Delivery) Harwood Academic Pub-lishers/Gordon and Breach Pubhshing Group Newark, NJ, 1995 6, 304. 

Dendrimers, dendrons and other dendritic systems have been synthesized as interesting compounds with a great potential in different biomedical applications, including delivery carriers of drugs, development of synthetic vaccines, antitumor systems or as therapeutic agents per se with, for example, antiviral and antibacterial properties. 

Esfand R, Tomalia DA (2001) Poly(amidoamine) (PAMAM) Dendrimers from Biomimicry to Drug Delivery and Biomedical Applications. Drug discovery today. 6 p. 427-436. 

S. Jana, S. Jana, Tamarind Seeds, Green Biomaterials from Biomedical and Drug Delivery Applications, Encyclopedia of Biomedical Polymers and Polymeric Biomaterials, Taylor Erancis, 2016, pp. 1-9, http //dx.doi.org/10.1081/E-ebpp-120053505. 

Chemical synthesis can even provide polyelectrolyte capsules with desired properties (luminescent, magnetic ones) for further biomedical or drug delivery applications, and also as catalyzed or fermentative microreactors. 

Chitosan is a natural cationic polysaccharide derived from chitin by partially deacet-ylating its acetamido groups with strong alkaline solutions [115]. Over the last two decades, chitosan has been used for various biomedical and drug delivery applications due to its low toxicity and good biocompatibility and antimicrobial and bioadhesive properties [116-118]. 

Laurencin C T, Ambrosio A M A, Borden M D and Cooper Jr J A, Tissue engineering orthop)edrc applications , Ann. Rev. Biomed. Eng., 1999, 1, 19-46. Laurencin C T, Ko F K, Borden M D, Cooper Jr J A, Li W J and Attawia M A, Fiber based tissue engineered scaffolds for musculoskeletal applications in vitro cellular response . In Biomedical Materials - Drug Delivery, Implants and Tissue Engineering, ed. T Neenan, M Marcolongo and R F Valentini, Materials Research Society, Warrendale, USA, 1999, 550, 127-35. 

Among other uses, these polymers have been employed in a variety of biomedical applications. Poly(phosphazenes) containing organic side chains, derived from the anaesthetics procaine and benzocaine, have been used to prolong the anaesthetic effect of their precursor drugs. They have also been used as the bioerodable matrix for the controlled delivery of drugs. 

Oppenheim, R. C., in Drug Delivery Systems Characteristics and Biomedical Applications (R. L. Juliano, ed.), Oxford University Press, New York, 1980. 

Improved characterization of the morphological/microstructural properties of porous solids, and the associated transport properties of fluids imbibed into these materials, is crucial to the development of new porous materials, such as ceramics. Of particular interest is the fabrication of so-called functionalized ceramics, which contain a pore structure tailored to a specific biomedical or industrial application (e.g., molecular filters, catalysts, gas storage cells, drug delivery devices, tissue scaffolds) [1-3]. Functionalization of ceramics can involve the use of graded or layered pore microstructure, morphology or chemical composition. 

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