Biomaterial chemical reaction technique

Another promising area for polymer development, as alluded to by Tirrell [5], is microelectronics. Plasma polymerization can be used to produce a polymeric coating directly on a substrate changing the composition of the gas feed allows a wide variation in the chemical composition of the surface produced [32], The same technique can also be used to modify surfaces for other applications, such as to improve the blood compatibility of biomaterials. The essential processes occurring in a plasma—mass transfer and reaction kinetics—have long been the domain of chemical engineers. 

A common route that can be applied for obtaining polyhydroxyalkanoates with desirable functionalities is to produce PHAs with terminal double bonds followed by chemical modification steps. Carbon double bonds are comparatively inert but can be easily transformed into reactive functional groups under mild reaction conditions. Non-functionalized PHAs can also be activated by surface modification techniques. The resulting tailor-made structural and material properties have positioned polyhydroxyalkanoates well to contribute to the manufacturing of second and third generation biomaterials. ... 

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