Bioluminescent bioreporter integrated circuits

Nivens, D.E. McKnight, T.E. Moser, S.A. Osbourn, S.J. Simpson, M.F. Sayler, G.S., Bioluminescent bioreporter integrated circuits Potentially small, rugged and inexpensive whole-cell biosensors for remote environmental monitoring J. Appl. Microbiol. 2004, 96, 33-46. 

BIOLUMINESCENT BIOREPORTER INTEGRATED CIRCUIT SENSING OF THE CHEMICAL AND BIOLOGICAL SPACECRAFT ENVIRONMENT... 

Figure 1. A bioluminescent bioreporter integrated circuit (BBIC)...

Simpson ML, Sayler GS, Patterson G, Nivens DE, Bolton E, Rochelle J, Amott C, Applegate B, Ripp S, Guillom MA. An integrated CMOS microluminometer for low-level luminescence sensing in the bioluminescent bioreporter integrated circuit. Sens Actuators B 2001 72 135-41. 

Ripp S, Daumer KA, McKnight T, Levine LH, Garland JL, Simpson ML, Sayler GS. Bioluminescent bioreporter integrated circuit sensing of microbial volatile organic compounds. J Ind Microbiol Biotechnol 2003 30 636-42. 

At the University of Tennessee s Center for Environmental Biotechnology, researchers are developing wireless biosensors that can be used to monitor microbial contamination and radiation exposure in future manned space missions. The researchers are using bioluminescent biosensor organisms built directly onto wireless integrated circuits. They call them Bioluminescent Bioreporter Integrated Circuits (BBIC). Bioluminescent... 

Bolton, E.K., et al.. Integrated CMOS Photodetectors and Signal Processing for Very Low-Level Chemical Sensing with the Bioluminescent Bioreporter Integrated Circuit. Sensors and Actuators B, 2002. 85 p. 179-185. 

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