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Biological pathways and networks

The importance of biological pathways and networks for predicting xenobiotic toxicity via toxicogenomics profiles has been demonstrated with various degree of success in recent years.26 Although the terms "pathway" and "network"... [Pg.292]

Building blocks, biological pathways, and networks Complex elements—from individual genes to entire organs— work together in a feat of biological teamwork to promote normal development and sustain health. These systems... [Pg.11]

The importance of pathways and networks was revealed by the study of the mechanisms of action of hormones, as well as by numerous studies on the mechanisms of oncogenesis and development. Biology articles and books... [Pg.181]

As shown in Fig. 1.1, the integration of pharmacogenomics and systems biology can help elucidate the mechanisms of diseases and drug actions at various levels and connect information between different levels. For example, altered genetic structure may cause malfunctions at the molecular level, which would influence the downstream interactions, pathways, and networks at the cellular level. Such changes may then lead to tissue or organ disorders that are disease phenotypes reflected as... [Pg.4]

In similar fashion to DNA and protein microarrays the ability to create arrays of cells and even tissues at high-density offers the potential for the development of cell-based sensors with extremely high throughput and multiplex capability. Research on biomolecular interactions on the genomic, the proteomic and the cellular level paves the way for advanced understanding of the function of the human genome and to unravel the complexity of biological pathways and cellular networks that control life processes. [Pg.94]


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See also in sourсe #XX -- [ Pg.292 , Pg.293 ]




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Biological networks

STATISTICAL NETWORK ANALYSIS FOR BIOLOGICAL SYSTEMS AND PATHWAYS

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