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Self-replication, biological models

Cellular automata are abstract discrete dynamical systems introduced by Von Neumann in an attempt to model self-replication in biological systems [11]. A cellular automaton consists of a set of nodes, usually arranged on a regular lattice, each of which supports state variables that take on a finite number of possible values. The state variables are synchronously updated at discrete... [Pg.610]

These examples have demonstrated that it is possible to use the templating properties of a compound to accelerate its own formation. This is a potentially very attractive approach for the production of large quantities of a specific product with high selectivity. Furthermore, synthetic self-replicating systems also provide interesting models for their biological counterparts, which in turn could provide important clues to understand chemical evolution and indeed the origin of life itself. [Pg.134]

What matters is that the genotype - the biological software - is a deposit of instructions and therefore is potentially capable of carrying the project of embryonic development. This was the long-awaited answer to vitalism, and the computer became therefore the new model of mechanism. In reality, the new model of a living machine is not the computer that we encounter in our daily life, but an ideal machine known as von Neumann s self-replicating automaton. [Pg.25]

In order to address the characteristics of biological models, we have to first define the basic principles of biological systems that a supramolecular model may mimic. Among the most important are selective molecular recognition of a molecular entity selective and highly accelerated modification of a substrate (typieal role of enzymes) compartmentalization and selective translocation of chemical species across boundaries (typieal role of biomembranes) harvesting and transformation of energy and self-replication. [Pg.101]


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