A Synthetic Self-Replicating System

5 -Amino-5 -deoxy-2, 3 -0-isopropylideneadenosine was acylated at N-S with an activated derivative of the 6-carboxy-2-naphthyl ester of Kemp s acid imide. The resulting molecule possesses self-complementary binding sites, the key feature of replicating molecules that act as templates for their own reproduction. The dimer of this molecule is, however, not very stable (K = 630 L mol-1). When the two initially mentioned educts are added, a small proportion of the ternary complex is also formed and undergoes a fast, template-catalysed 

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A synthetic self-replicating system by Kiediowsky el at Figure 6.16. Examples of host-catalyzed reactions. 

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