Biological computation transfer functions

RNA structures, compared to the helical motifs that dominate DNA, are quite diverse, assuming various loop conformations in addition to helical structures. This diversity allows RNA molecules to assume a wide variety of tertiary structures with many biological functions beyond the storage and propagation of the genetic code. Examples include transfer RNA, which is involved in the translation of mRNA into proteins, the RNA components of ribosomes, the translation machinery, and catalytic RNA molecules. In addition, it is now known that secondary and tertiary elements of mRNA can act to regulate the translation of its own primary sequence. Such diversity makes RNA a prime area for the study of structure-function relationships to which computational approaches can make a significant contribution. 

The 17r<7 states also dominate the photoinduced processes in hydrogen-bonded chromophore-solvent clusters. The photoinduced hydrogen transfer reaction is experimentally and computationally well documented in clusters of phenol and indole with ammonia [14,16,32], There is no clear evidence for the existence of an excited-state proton transfer process in these systems [14], The same conclusion applies to bi functional chromophores solvated in finite clusters, such as 7HQ-ammonia and 7HQ-water clusters [15]. In future work, the photochemistry of larger and biologically relevant chromophores (such as tyrosine, tryptophan, or the DNA bases) should be investigated in a finite solvent environment. 

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