Bioimaging synthesis

Liu XJ, Knauer M, Ivleva NP, Messner R, Haisch C (2010) Synthesis of core-shell surface-enhanced Raman tags for bioimaging. Anal Chem 82 441 146... 

W-C. Law, K.-T. Yong, 1. Roy, H. Ding, R. Hu, W.W Zhao, P.N. Paras, Aqueous-phase synthesis of highly luminescent CdTe/ZnTe core/shell quantum dots optimized for targeted bioimaging. Small 5 (2009) 1302-1310. 

Santra, S., Yang, H., Holloway, P.H., Stanley, J.T., Mericle, R.A. Synthesis of water-dispersible fluorescent, radio-opaque, and paramagnetic CdS Mn/ZnS quantum dots a multifunctional probe for bioimaging. J. Am. Chem. Soc. 127, 1656-1657 (2005)... 

Iridium(lll) complexes, especially those with polypyridine ligands, as therapeutic and bioimaging reagents for cellular applications 12RCA12069. Isolation, biological activity and synthesis of the natural anticancer product eUipticine and related pyridocarbazoles 12RCA8883. 

Seisenbaeva GA, Kessler VG, Pazik R, Strek W. Heteroleptic metal oxide oxoclus-ters as molecular models for the sol-gel synthesis of perovskite nanoparticles for bioimaging apphcations. J Chem Soc Dalton Trans 2(X)8 14(26) 3412—21. 

Kessler GV. The chemistry behind the sol-gel synthesis of complex oxide nanoparticles for bioimaging applications. J Sol-Gel Sci Technol 2009 51 264-71. 

For applications in ultrafiltration membranes, bioimaging, and diagnostics, a special method of synthesis of PVB has been suggested (20). There, swollen PVA particles are added to a butyraldehyde solution in ethanol. This methods gives polymers with high contents of butyral moieties up to 84%. 

Finally, a possible application is the design of luminescent probes for bioimaging in animals, which is nowadays being carried out using lanthanide nanoparticles. For these applications the in-depth excitation of the luminescent probes is challenging and leads to the development of two-photon excitation [162]. This amount of new potential applications will still drive the synthesis of new photoactive lanthanide complexes and continue to stimulate the inventiveness of researchers in this field. 

Ge QDs can be synthesized with both the solvent method and the sol-gel method. The maximum emission varies from 800 nm to 1200 nm and the QY from 0.05% to 8% according to the QD size or synthesis methods. The emission spectra of Ge QDs are rather wide. Furthermore, they are easily oxidized and a core-shell structure is not yet available, so as yet there are no reports on the conversion of Ge QDs into the aqueous phase or their application in bioimaging. " ... 

In summary, the synthesis of high-quality and low-toxicity QDs is a prerequisite for the use of NIR QDs in bioimaging. Current research focuses on the development of synthesis methods in aqueous solution for QDs without toxic elements. More effort should be focused on novel methods that take... 

---