Molecular bioengineering

University of Washington Center for Bioengineering Molecular Bioengineering Program Box 351750... 

Department of Molecular Biosdences and Bioengineering, University of Hawaii of Manoa, Honolulu, Hawaii, USA... 

Lee, E.Y. and Shuler, M.L. (2007) Molecular engineering of epoxide hydrolase and its application to asymmetric and enantioconvergent hydrolysis. Biotechnology and Bioengineering, 98, 318-327. 

Onda, M., Ariga, K. and Kunitake, T. (1999) Activity and stability of glucose oxidase in molecular films assembled alternatively with polyions. Journal of Bioscience and Bioengineering, 87, 69-75. 

Yu SJ (1989) Purification and characterization of gluathione S-transferase from five phytophagous Lepidoptera. Pestic Biochem Physiol 35 97-105 Yu SJ (1992) Plant allelochemical-adapted glutathione transferases in Lepidoptera. In Mullin CA, Scott JG (eds) Molecular mechanisms of resistance to herbivorous pests to natural, synthetic and bioengineering control agents. Plenum, New York, pp 174-190 Yu SJ (1996) Insect glutathione S-transferases. Zool Stud 35 9-19... 

Once isolated, the natural H2 producers can be optimized by conventional mutagenesis, and they should be studied so that we can understand those features that make them the best H2 producers. This characterization would involve the analysis of metabolic fluxes (Stephanopoulos and Sinskey 1993 Schuster et al. 1999) and molecular genetics. It would result in new, previously unknown adaptations necessary for improved H2 production, and could provide information on the most important mutations that are required to obtain excellent H2 producers. Information obtained from these experiments should be used in genetic engineering approaches for optimizing H2 producers. Moreover, excellent H2 producers should be used in bioengineering approaches. 

Jaeger, K.E. and S.Wohlfarth. (1993) Bacterial lipases Biochemistry, molecular genetics and applications in biotechnology. Bioengineering, 9, 39-46. 

Laboratory of Molecular Enzymology, Graduate School of Bioengineering, Soka University, Tokyo, Japan... 

Featuring end-of-chapter exercises, with problems ranging in scope from straightforward calculations to small computational simulation projects, this book will be suitable for advanced undergraduate or graduate level courses in systems biology, computational bioengineering, and molecular biophysics. 

Department of Molecular Biosciences and Bioengineering University of Hawaii at Manoa Honolulu, Hawaii... 

In addition, the subject of assembly looms as an apparently insurmountable obstacle. It is not at all clear how researchers would go about assembling individual molecular components into a functioning device, although bioengineering offers a potential solution to this problem. Examples of self-assembled structures exist everywhere in nature from the helical secondary structure of DNA to the human brain. Current knowledge of such systems is simply inadequate to allow scientists to employ similar forces to create synthetic molecular electronic devices. Clearly, an enormous amount of groundwork needs to be laid if the concept of the molecular electronic device or biochip computer is ever to become a reality. 

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