Bioconjugates, supramolecular

Niemeyer, C M, Sano, T, Smith, C L, and Cantor, C R (1994) Oligo-nucleotide-directed self-assembly of proteins semisynthetic DNA-strepta-vidin hybrid molecules as connectors for the generation of macroscopic arrays and the construction of supramolecular bioconjugates. Nucleic Acids Res. 22, 5330-5339. 

Streptavidin supramolecular bioconjugates (for reviews see [11,46-48]) Smart streptavidins (for review see [49-51])... 

Self-assembly phenomena based upon secondary forces have been widely observed in biological systems such as DNA, viruses, bacterial cell surface layers etc [70-73]. Nature-made supramolecular objects are very sophisticated in size and shape, and show tremendous specific and efficient functions. For example, we know many enzymes are responsible for specific catalytic processes. In this context, creation of supramolecular architectures with biomimetic or bioconjugate features would be desirable and worth investigating. In particular, a few examples related to the title of this review article have been reported. 

It is also interesting that rod assemblies can be apphcable to biomimetic or bioconjugate systems, hi Sect. 2.7, artificial nucleic acid complexes consisting of amphiphihc rods and linear nucleic acid polymers showed single twisted right-handed hehcal fibers. In addition, carbohydrate-coated supramolecular objects self-assembled by rod-coils or wedge-coils revealed outstanding fig-... 

Rodell, C.B., Mealy, J.E., Burdick, J.A., 2015. Supramolecular guest-host interactions for the preparation of biomedical materials. Bioconjug. Chem. 26 (12), 2279-2289. 

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