Biocompatibility mechanical compatibility

Newly developed injectable CNTs will require both in vitro and in vivo testing to determine biocompatibility, blood compatibility, mechanical stability, and safety (Pearce et al., 2007). Here, we review the current articles on toxicity of CNTs and in vivo barriers. 

In vivo testing in animal models is essential for implanted biomaterial devices (e.g., scaffolds) to determine biodegradation, mechanical compatibility, FBR, and biocompatibility of the material with host tissue or device function. 

The results by Hetrick et al.32 support the use of NO-release coatings for developing more tissue-compatible sensors. However, the impact of NO on the biocompatibility at a NO-releasing implant is a multifaceted question that is still not fully understood. Further study into the mechanisms by which NO decreases tissue encapsulation and chronic immune response while increasing angiogenesis will aid in optimization of the NO release properties (e.g., flux, concentration, and duration) of an implant coating for sensor applications. 

The advent of high-strength carbon-based fibers has led to a number of structural applications in medical treatment. The specifications for implanted materials required that they offer acceptable long-term mechanical properties and surfaces that are biocompatible [126]. Surface compatibility affects immediate acceptance, while the long-term mechanical performance is determined by the bulk properties of the implant. 

An absorbable polymeric modifier that is compatible with the chosen cyanoacrylate to achieve a moderate-to-high preuse viscosity for ease of application, and to increase the absorption rate and compliance of tile cured adhesive for minimizing residence time at the application site and maximizing mechanical biocompatibility — for this, highly absorbable liquid oxalate polymers, such as poly(triox-yethylene oxalate) (PTOEO) and amorphous or low-melting absorbable copolyesters such as those described in Chapter 3 — polyaxial copolyesters and other copolymers based on cyclic monomers — were selected. 

Biocompatibility Acceptance of an artificial implant by the siurounding tissues and as a whole. The implant should be compatible with tissues in terms of mechanical, chemical, surface, and pharmacological properties. 

Biocompatability Compatibility with Hving tissue, for example, in consideration of toxicity, degradability, and mechanical interfacing. 

This chapter addresses the application of polymeric biomaterials in the context of implantable devices intended for long-term functionality and permanent existence in the recipients. Basic concepts of biocompatibility as well as mechanical and structural compatibility are discussed to provide appropriate background for the understanding of polymer usage in cardiovascular, orthopedic, ophthalmologic, and dental prostheses. Furthermore, emerging classes... 

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