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Biochemistry of Platelet Activation

Anita Ryningen and Holm Holmsen Department of Biochemistry and Molecular Biology University of Bergen NORWAY [Pg.188]

Few seconds later more platelets are deposited on the collagen fibrils and the platelets are now also sticking to each other (platelet aggregation). A growing platelet plug is formed in the lesion of the vessel wall as more platelets aggregate. At a certain stage in diis process, red blood cells are no [Pg.188]

Anita Ryningen has done research since 1991 until the present on signaling mechanisms involved in activation and inhibition of platelet responses at the Department of Biochemistay and Molecular Biology, University of Bergen. She is currendy finaliTing her Ph. D. thesis. Holm Holmsen is Professor at the same institution and received his Dr. Phil, from the University of Oslo in 1969 on adenine nucleotide metabolism in platelets. He continued these studies at the Department of Medicine, Temple University Medical School, Philadelphia (1970-1982). His current research interest is lipid-mediated, cellular signal transduction. [Pg.188]


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