Hormones Comparative biochemistry

Minor changes in the stereochemistry and substitution pattern of the steran skeleton result in vastly different yet specific physiological and pharmacological effects, which in turn influence developmental, metabolic, and behavioral phenomena. The organic chemistry and biochemistry of steroids is the subject of many excellent books and an enormous amount of research and patent literature. This chapter compares and contrasts the structure and mode of action of various steroids, their role in regulating hormonal secretion, and the timing of this regulatory action. 

Leatherland, J.F., McKeown, B.A. and John, T.M. (1974). Circadian rhythm of plasma prolactin, growth hormone, glucose and free fatty acid in juvenile kokanee salmon, Oncorhynchus nerka. Comparative Biochemistry and Physiology 47A, 821-828. 

Nichols, J.R. and Fleming, W.R. (1990). The effects of salinity, hypophysectomy and hormone administration on gill RNA metabolism of the eury haline teleost FurOdulus kansae. Comparative Biochemistry and Physiology 95A, 121-126. 

Antagonist In biochemistry, a substance that counteracts the cellular effects of a natural compound (such as a hormone or neurotransmitter) by binding to the cellular receptor for the compound and blocking its action. Compare Agonist. 

Bewley, T. A., H. Kawauchi, and C. H. Li Human Pituitary Growth Hormone. XXXIII. Comparative Studies of the Single Tryptophan Residue in Human Chorionic Somatotropin and Human Pituitary Growth Hormone. Biochemistry 11, 4179-4187 (1972). 

---