Biochemistry and the Organization of Cells

The protocols are grouped into six sections Chromosomes, Cell Biology, Molecular Biology, Genomics, Biochemistry, and The Organism. Several of the protocols assume a knowledge of basic molecular techniques and may require users to refer to one of the... 

Thus we shall be concerned with properties that furnish information about the nature of the ligands, the oxidation state of the metal, and the geometry of the field of ligands. Techniques such as radio-isotope tracer studies, neutron-activation analysis, and electron microscopy are powerful methods for locating a metal within constituents of the cell and are particularly suited to heavy-metal rather than organic drugs but since they do not provide information about the chemical environment of the metal they will not concern us here. After each section below we shall give an example, not necessarily from platinum chemistry, where the method has been used with success in biochemistry. 

Bioanalysis may be defined as laboratory analysis of biomolecules. Biomolecules, in turn, are organic compounds with biological activity, generally important only in biological systems, or cells. Biochemistry is the study of structure and function of biomolecules. Biotechnology, a related concept, concerns the industrial applications of biochemical techniques. Thus bioanalysis, biochemistry, and biotechnology are closely related concepts, all concerned primarily with biomolecules. 

Pier Luigi Luisi became Professor Emeritus (Macromolecular Chemistry) at ETH-Ziirich in 1982, where he also acted as Dean of the Chemistry Department he is currently aprofessor of Biochemistry at the University of Rome 3. He has authored c. 300 papers in the fields of enzymology, molecular biology, peptide chemistry, self-organization and self-reproduction of chemical systems, and models for cells. 

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