Bioceramic simulated body fluids

Structure of calcium titanate/titania bioceramic composite coatings on titanium alloy and apatite deposition on their surfaces in a simulated body fluid. Surf. Coat. Technol., 201, 8715-8722. 

Himeno, T., Kawashita, M., Kim, H.-M., Kokubo, T., and Nakamura, T. (2001). Zeta-potential variation of bioactive titanium metal during apatite formation on its surface in simulated body fluid. Bioceramics, Vol. 14, pp. 641-644, Brown, S., Clarke, I., and WiUiams, P., eds., Switzerland Trans Tech Puhlications Ltd. 

Solubility of As-Synthesized CaTiZr3(P04)6 Figure 10.18 shows solubility data of several bioceramic materials in protein-free simulated body fluid (pf-SBF after Kokubo 1996). The highest solubihty was found for a-TCP, followed by HAp. The CaTiZr3(P04)6 exhibited the lowest solubility, and hence was considered to be a biomaterial of the second generation, with extreme hiostability (Szmulder-Moncler et al., 1992 Schneider et al., 1998 Schneider, 2002). 

Nevertheless, recently studies of new materials of TZP, doped with yttria tested in simulated body fluids and in animals, have shown slight decreases in fracture toughness and Young Modulus [34-36]. The observed strength, after two years, is sill much higher that the strength of alumina bioceramic tested under similar conditions. Because the zirconia/zirconia... 

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