Fermentation biocatalysis, complex

Since pharmaceuticals are becoming increasingly complex molecules, we will keep strengthening our science base in this area too, by combining our internal skills with relevant external expertise in fermentation, biocatalysis, biotransformation, and chemical synthesis. 

In earlier papers from this laboratory, we have proposed the terms "Controlled Catalytic Biomass" and "Structured Bed Fermentation" to describe immobilized cell systems effecting complex biocatalysis (1,2). The meaning of these terms is obvious when one considers the biocatalyst in relation to its microstructure, predesigned catalytic reactor design, and controlled catalytic activity vis-a-vis cellular reproduction. Some of the potential advantages of such a catalytic system are summarized in Table I. 

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