Binary systems relation between activity coefficients

The binary interaction parameters are evaluated from liqiiid-phase correlations for binaiy systems. The most satisfactoiy procedure is to apply at infinite dilution the relation between a liquid-phase activity coefficient and its underlying fugacity coefficients, Rearrangement of the logarithmic form yields... 

The Gibbs-Duhem equation for ternary mixtures is used to analyze the quality of experimental data pertaining to the solubility of drugs and other poorly soluble solids in a binary mixed solvent. In order to test the quality of the data, a thermodynamic consistency test is suggested. This test is based on the thermodynamic relation between the solubilities of a solid in a binary mixed solvent at two different compositions and the activity coefficients of the constituents of the solute-free mixed solvent. The suggested test is applicable to all kinds of systems with the following limitations (1) the solubility of the solid should be low, (2) the above two compositions of the mixed solvent should be close enough to each other. 

In a quasi-binary system, interdiffusion of ions also results in a so-called interdiffusion diffusion that is also rate-limited by the diffusivity of the slower of the two ions. This process occurs, e.g., when solid-state reactions between ceramics or ion-exchange experiments are carried out. Solid electrolytes can be used as sensors to measure thermodynamic data, such as activities and activity coefficients. The voltage generated across these solids is directly related to the activities of the electroactive species at each electrode. 

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