Bilirubin in serum

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Li X, Rosenweig Z. A fiber-optic sensor for rapid analysis of bilirubin in serum. Anal Chim Acta 1997 353 263-73. 

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Jaundice Indicates that there is an elevated concentration of bilirubin in serum. 

Bilirubin in serum Hypersil ODS Acetonitrile /dimethylsulphoxide /water (40 40 20) UV 450 nm 141... 

In pernicious anemia, the bone marrow is hyperplastic and contains many large young cells which are designated megaloblasts. The peripheral blood shows severe macrocytic anemia, leucopenia with a high percentage of old polymorphonuclear leucocytes, and thrombocytopenia. Erythrocyte destruction is excessive, as manifested by an increase in the level of bilirubin in serum and a rise in urobilin excretion in the urine. An abnormality of tyrosine metabolism is demonstrated by the excretion of certain phenolic compounds in the urine. Hydrochloric acid is absent from the gastric juice. 

A commonly used method for the estimation of total and conjugated bilirubin in serum. It is based on the diazotization of bilirubin by diazotized sulphanilic acid to azobilirubin which is coloured blue in alkaline solutions. Caffeine-sodium benzoate is... 

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