Bifidobacterium linoleic acid

Alternatives to using ruminant foods to provide CLA in the diet are of great interest to the food-processing industry, perhaps most so in dairy processing. Sieber et al (2004) reviewed the impact of microbial cultures on CLA in dairy products. Several strains of Lactobacillus, Propionibacterium, Bifidobacterium, and Enterococcus are able to form CLA from linoleic acid lactic acid bacteria and propionibacteria appear to show promise to increase CLA during ripening of cheese. Presently, data are not convincing that this... 

Production of free conjugated linoleic acid by fermentation performed using Lactobacillus casei and Bifidobacterium bifidum. Global Vet, 14 (5), 720-728. 

Chung, S.FL, Kim, I.H, Park, H.G., Kang, H.S. et al (2008) Synthesis of conjugated linoleic acid by human-derived Bifidobacterium breve LMC 017 utilization as a functional starter culture for milk fermentation. ). Agric. Food Chem., 56, 3311-3316. 

CLA can also be synthesised in the human colon. Some bacterial strains normally present in the human large intestine (Lactobacillus, Propionibacterium and Bifidobacterium species and some Clostridium-like bacteria) have been found to metabohse linoleic acid and form CLA that is converted further to trans-1118 1 in vitro. Vaccenic acid may be also a precursor of rumenic acid (cis-9,trans-ll CLA) in human tissues (Devillard, McIntosh, Duncan, Wallace, 2007). 

Coakley M, Ross RP, Nordgren M, Fitzgerald G, Devery R, Stanton C. Conjugated linoleic acid biosynthesis by human-derived Bifidobacterium species. / Appl Microbiol. 2003 94 138-145. 

Gut bacteria also contain other enzymatic activities, not least linoleic dehydrogenase which converts alpha-linoleic acid to conjugated linoleic acid (CLA), a beneficial fat linked to protection from CVD and certain cancers through improved immune function. Wall et al. (2010) have also shown that feeding alpha-linoleic acid together with the probiotic strain Bifidobacterium breve NCIMB 702258, a common intestinal commensal... 

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