Beta-santalol

Betanin [7659-95-2 Beta receptors Beta-santalol [77-42-9] Betavel Betaxan thins... 

Santalum album L. S. myrtifolium Roxb. S. verum L. Tan Xian (Sandalwood) (heartwood) Alpha-santalol, beta-santalol, alpha-santalene, beta-santalene, santene, alpha-santenone, alpha-santenol, santalone, santalic acid, teresantalic, isovaleraldehyde, teresantalol, tricycloekasantal, santalin, deoxysantalin, sinapyl aldehyde, caniferyl aldehyde, syringic aldehyde.33 Treat stomachache. 

The East Indian sandalwood oil probably represents one of the most precious perfumery natural raw materials because of the rarity of the natural plants from which it is extracted. As until recently [36] since no industrially viable process existed for production of (Z)-beta-santalol, the main olfactive constituent of Indian sandalwood (see Fig. 6), the focus was directed toward the search for cheaper synthetic analogs in order to also prevent resource depletion. Alpha-campholenic aldehyde derivatives are clearly affording the best, and most often used substitutes for such a natural resource [37]. 

Z)-beta-santalol (R)-alpha-campholenic aldehyde Fig. 6 Natural sandalwood odorant (—)-(Z)-beta-santalol and alpha-campholenic aldehyde... 

For example, rearrangement of a-pinene oxide produces, among the ten or so major products, campholenic aldehyde, the precursor of the sandalwood fragrance santalol. The conventional process employs stoichiometric quantities of zinc chloride but excellent results have been obtained with a variety of solid acid catalysts (see Fig. 2.23), including a modified H-USY [70] and the Lewis acid Ti-Beta [71]. The latter afforded campholenic aldehyde in selectivities up to 89% in the liquid phase and 94% in the vapor phase. 

---