3-Benzylthio-5-phenyl

R - CH2 C6H5 Aminosulfenyl-benzylthio-phenyl-essigsdure R = C6H5 Aminosulfenyl-phenyl-phenylthio-... 

Some authors exemplified different regioselectivity on glycosylations of various O- and thio-p-D-glycopyranosides (phenyl, benzyl, phenylethyl, phenylthio, benzylthio, etc.), including a C-glycosyl compound.29... 

Quite similarly, the reaction product obtained from 2-benzylthio-3-phenylquinazolin-4(3H)-thione and hydrazine should be assigned the structure 2-anilino-3-aminoquinazoline-4(3//)-hydrazone instead of the reported 2-hydrazino-3-phenyl quinazoline-4(3//)hydrazone (Scheme III.23) (70IJC1055). 

A convenient route to 2-alkylthio-4-alkyl-4-hydroxy-5,6-dihydro-4/7-l,3-thiazine derivatives 176 is the reaction of A-alkyldithiocarbamates with a,/3-unsaturated ketones in the presence of boron trifluoride etherate at 0°C (Scheme 15) <2002HAC377>. The predominant diastereomer displayed a m-relationship between the hydroxyl group and the C-4 substituent. Subsequent dehydration led to two isomeric products 177 and 178 with an equilibrium mixture resulting in a ratio of 94 6 in the case of 2-benzylthio-4-hydroxy-4-methyl-5,6-dihydro-4/7-l,3-thiazine. 2-Phenyl-4-alkyl-4-hydroxy-5,6-dihydro-4/7-l,3-thiazine derivatives are similarly prepared by reacting thio-benzamide with o ,/3-unsaturated ketones at room temperature <2002EJP307>. 

Thiazolidine-2-thione, 3-allyl-, 56, 79 2-Thiazohne, 2-allylthio-, 56, 77 2-Thiazoline, 2-benzylthio-, 56, 82 2-Thiazoline, 2-cmnamylthio-, 56, 82 2 Thiazoline, 2 ethylthio, 56, 82 2-Thiazohne 2-mercapto-, 56, 77 2-Thiazoline, 2-methylthio-, 56, 82 2-Thiazohne, 2-(4-phenyl-l-buten-3-yl)-thio-, 56, 78... 

Amino-3-benzylthio- XV/I, 736 2-Amino-3-mercapto- -benzylester (Hydrochlorid) XI/2, 357 Sulfoximid S-(2-Acetyl-4-methyl-phenyl)-S-methyl- Ell, 1303 (RjSO + HN3)... 

Methan Imino-(2-methyl-phenyl)-(2-thienyl)- XIII/2a, 357 f. Pyridin 2-Benzylthio- El 9a, 449 (COOH -v SR)... 

QH, CH(CH3)2 ch2-c6h5 K K K CN CO-NH-COOC2lI5 CH=CH-CN —< )—no2 co-ch3 Cl Cl Br Cl Cl Aceton/(H5C2)3N Ethanol/(H5C2)3N Ethanol/(H5C2)3N Aceton/(H5C2)3N Ethanol/(H5C2)3N Ruckfl. Ruckfl. Ruckfl. Ruckfl. Ruckfl. 0,5 0,52 1,5 3 2,25 4-Amino-5-cyan-2-propylthio-... 4-Amino-5-(ethoxycarbonyt-aminocarbonyl)-2-isopropylthio-... 4-Amino-2-benzylthio-5-(2-cyan-ethenyl)-... 4- Aminv-2-benzytthio-5-(4-nitro-phenyl)-... 5- Acetyl-4-amino-2-benzylthio-... 79 55 46 48 80 111,5 114-118 156 140 116 737 733. 764 725 881 758... 

MorphoHno-5-(4-nitro-phenyl)-l,3-thiazol880 Eine Suspension von 3.85 g (0,01 mol) N -[Chlor-(4-nitro-benzylthio)-methylen]-N,N-dimethyl-formamidinium-perchlorat in 8 ml Acetonitril wird tropfenweisc un-ter Riihren mit 1,74 g (0,02 mol) Morpholin versetzt und anschlicflend kurz aufgekocht. Nach Zugabe von 2 ml Triethylamin erhitzt man weitere 15 min unter RuckfluB. Nach Abkiihlen wird das Endprodukt abgesaugt und aus Acetonitril umkristallisiert Ausbeute 1,5 g (51%) Schmp. 203-205°. 

Benzyl-2-phenyl-5-trifluoracetamino- 123 2-Benzyl-4-(2-pyrazinyl)- 31 2-Benzyl-5-(4-pyridyl)- 110 2-Benzylthio-4-carboxy-5-hydroxy- 121... 

Benzylthio-4-ethoxycarbonyl-2-methylthio- 147 2-Benzylthio-5-hydroxy- 328 2-Benzylthio-5-melhyl- 195 5-(4-Biphenylylcarbonyl)-2-ethoxy-4-phenyl-138 5-(4-Biphenylyloxy)-2-(4-methyl-phenyl)-4-tri-... 

Amino-2-benzylthio-5-phenyl- 194 3-Amino-2-methylthio-5-plicnyl- 194 3-Benzyl-2,5-diphenyl- 205 2-[2-(3-Butenyloxy)-phenyl]-3,5-diphenyl- 105... 

Amino-5-(4-chlor-phenyl)-4-methyl- 325 5-(2-Benzoyloxy-ethyl)-4-methyl- 207 2-Benzylthio-4-phenyl-... 

Allylthio-5,7-dihydroxy- 923 2-Amino-5,7-dihydroxy- 871 2-Amino-5,7-dimethyl- 878 5-Amino-2,7-diphenyl- 924 2-Amino-7-hydroxy-5-mercapto- 918 5-Amino-2-(4-methoxy-phenyl)-7-phenyl- 924 2-Benzylthio-5,7-dihydroxy- 923 2,5-Diamino-7-hydroxy- 908... 

Dithiadiazines (84) are obtained by reacting S-benzyl-isothiosemicarbazide with aryl isothiocyanates to yield the intermediate 5-S -benzylthio-l-phenyl-2-thiohydrazodicarbonamides (83), which are oxidatively cyclized with bromine (Equation (13)) <88H(27)2373>. 

Dihydrobenzo[b]thiophene may be obtained by reduction of ben-zo[b]thiophene (Section III,A,1) by treating 2-o-(benzylthio)phenyIethanol with SOCl2-pyridine (91%),208 and by cyclization of o-(methylthio)phenyl-carbene at 250°C (45%) the last procedure is mainly of academic interest.304 Substituted phenyl vinyl sulfides undergo photocyclization to the expected... 

From 3-amino-2-benzylthio-4-phenylthiazolium bromide (340) and arylthiocyanates in the presence of triethylamine 2-arylamino-5-phenyl-thiazolo[2,3-6][l,3,4]thiadiazolium bromides (53) are formed. In dimethylformamide as solvent the yellow mesoionic compounds anhydro-2-arylamino-5-phenylthiazolo[2,3-6][l,3,4]thiadiazolium hydroxides (54) are obtained (Scheme 31) <88S729>. 

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