Benzylidene acetophenone, reaction with

Tetraazafulvalenes bearing two pyrazole subunits could be prepared by an original way. Tlius, treatment of benzylidene acetophenone with iso-pentylnitrite leads to an A, A -dihydroxy-bipyrazolyl-A, A -oxide, which in turn can be oxidized to TAF of type 100 (72CC961, 79JOC3211). Another type of oxidative dimerization was observed by the reaction of the electron-rich l-methyl-2,4-bis(dimethylamino)imidazole with silver salts (83TL3563). A bis-cation was isolated in 30% yield in the presence of sodium tetrafluo-roborate an unsymmetrical structure 101 was predicted from its NMR data (Scheme 40). 

The Michael reaction of benzylidene acetophenone and benzylidene acetone with ethyl acetoacetate, nitromethane, and acetylacetone was studied by Musaliar and co-workers in the presence of a cetyltrimethy-lammonium bromide-containing aqueous micellar medium.50 The Michael reaction of various nitro alkanes with electrophilic alkenes is performed in NaOH (0.025-0.1 M) in the presence of cetyltrimethylam-monium chloride (CTACI) without any organic solvent (Eq. 10.23).51... 

In a lOmL round-bottomed flask equipped with a magnetic stirrer bar were placed tetrahydrofuran (0.8 mL) and immobilized poly-D-leucine (100 mg). (7 )-Benzylidene acetophenone (50 mg), l,8-diazabicyclo[5.4.0] undec-7-ene (90 mg), and urea-hydrogen peroxide (27 mg) were added to the mixture. The thick white reaction mixture was stirred vigorously for 30 minutes. 

In a first model reaction, Danopoulos et al. [472] reacted a free pincer carbene ligand with [RuCPPhjljCl ] and obtained the corresponding octahedral pincer carbene adduct (see Figure 3.156). The complex lacks the yhdene functionality necessary for activity of the complex in olefin metathesis. Instead, the compound was successfully employed in the transfer hydrogenation of cyclohexanone, acetophenone and benzylidene anihne. Reaction temperatures were mostly low to moderate (25-55 °C) and catalyst loadings in the range of 0.015 to 0.1% with TONs of only 150 to 8800. 

Many references to kinetic measurements may have already been covered earlier with other physical methods. These include studies on pseudorotation of stereoisomers of a 10-P-5 spirophosphorane, on the formation rate of acylpho-sphonate hemiketals, on the rate of decomposition of hydroperoxides formed by the oxidation of soya phosphatidylcholine, on the kinetics of the reaction of trimethyl phosphite with benzylidene acetophenones, calorimetric studies on the reaction kinetics of dithiophosphoric acid 0,0 -dialkyl esters with zinc oxide, " and the kinetics of selective dephosphorylation of 2 -phosphorylated and 2 -thiophosphorylated dinucleotides. 

Diamino-4-phenylimidazole reacts with aromatic a,/3-unsaturated ketones in an acidic medium to yield triazepines 436 (83KGS93). If the reaction is carried out in alkaline medium with benzylidene acetophenone,... 

Dithiins are produced by the reactions of geminal dithiols with enones such as chalcone and benzylidene acetophenone (Equation (54)) <62JOC4488, 66BSF1920>. Treatment of geminal dithiols with malononitrile also gives rise to 1,3-dithiins (Equation (55)) <62JPR2ll>. 

Yan et al. (2007) reported that polysubstituted annulated pyridines can be synthesized in high yields by four-component, one-pot cyclocondensation reactions of N-phenacyl pyridinium bromide, aromatic aldehydes, acetophenones or cyclic ketones in the presence of ammonium acetate and acetic acid, assisted by microwave irradiation. Cyclic ketones with two a-CH groups yield annulated pyridines with additional a-benzylidene groups, which are derived in situ from double aldol condensation of cyclic ketones with two moles of aromatic aldehydes. 

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