Benign prostatic hyperplasia complications

Surgical intervention should be reserved for patients with severe lower urinary tract symptoms of benign prostatic hyperplasia or those with complications of disease (such as recurrent urinary tract infections, renal failure, and bladder calculi). 

When monitoring efficacy of drug treatment for benign prostatic hyperplasia, subjective endpoints include relief of obstructive and irritative voiding symptoms. Objective endpoints include improvements of urinary flow rates, decreased post-void residual urinary volume, and decreased complications of disease. 

TABLE 49-2. Objective Tests Used to Assess the Size of the Prostate and Complications of Benign Prostatic Hyperplasia (BPH)... 

Benign prostatic hyperplasia (BPH) is one of the most common problems of elderly men, affecting more than 40% of men over age 70. BPH results in the urinary symptoms of hesitancy and frequency. Since prostate cancer affects a similar age group and often has similar presenting symptoms, the presence of BPH often complicates the diagnosis of prostate cancer, although it does not appear to increase the risk of developing prostate cancer.2,5... 

In a condition such as benign prostatic hyperplasia, common complications are reduced libido, a reduced volume of ejaculate, and impotence within 3 days of starting treatment, serum testosterone can reach castration concentrations. 

Facio F, Kashiwabuschi R, Nishi Y, Leao R, McDonnell P, Burnett A. Benign prostatic hyperplasia. Clinical treatment can complicate cataract surgery. Int Braz J Urol 2010 36(5) 563-70. 

Fine SR, Ginsberg P. Alpha-adrenergic receptor antagonists in older patients with benign prostatic hyperplasia issues and potential complications. J Am Osteopath Assoc 2008 108(7) 333-7. 

Kaplan SA, Chung DE, Lee RK, Scofield S, Te AE. A 5-year retrospective analysis of 5a-reductase inhibitors in men with benign prostatic hyperplasia finasteride has comparable urinary symptom efficacy and prostate volume reduction, but less sexual side effects and breast complications than dutasteride. Int J Clin Pract 2012 66(ll) 1052-5. 

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