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Benemide - Probenecid

In those with gout, the serum uric acid level is usually elevated. Sulfinpyrazone increases the excretion of uric acid by the kidneys, which lowers serum uric acid levels and consequently retards the deposit of urate crystals in the joints. Probenecid (Benemid) works in the same manner and may be given alone or with colchicine as combination therapy when there are frequent, recurrent attacks of gout. Probenecid also has been used to prolong the plasma levels of the penicillins and cephalosporins. [Pg.187]

Primidone (Mysoline) Anticonvulsant Probenecid (Benemid) Anti-gout... [Pg.47]

Probenecid (Benemid, Others) [Uricosuric/Analgesic] Uses ... [Pg.264]

Pentobarbital Butylone , Nembutal , Probenecid Benemid , Probalan ... [Pg.377]

Penicillins and Probenecid. A number of organic acids are actively transported from the blood into the tubular urine and vice versa. In some situations, these agents interfere with each other s excretion. Probenecid (e.g., Benemid) can increase the serum concentrations and increase and prolong the activity of penicillin derivatives by blocking their tubular secretion. This is an interaction that has been used to therapeutic advantage in the treatment of certain infections. [Pg.1399]

Probenecid (Benemid) (increases excretion of uric acid)... [Pg.153]

Understand that the healthcare provider might prescribe that probenecid (Benemid) and cephalosporin are to be taken together. The goal is to extend the half-life of cephalosporin without having to increase the dose. [Pg.153]

Probenecid (e.g., Benemid) Inhibits renal reabsorption of uric acid. Tophaceous gout. To enhance the duration of penicillin (Fig. 7.13) May exacerbate gout attacks. Otherwise well tolerated. ... [Pg.136]

Two other dmgs affected by penicilhn are methotrexate (Folex) and probenecid (Benemid). There is a decrease in the body s abihty to clear methotrexate when penicilhn is present. There can be a build up of methotrexate resulting in toxicity. [Pg.238]

Probenecid (Benemid) may extend the half-Mfe of cephalosporins and can result in toxicity. However, cephalosporins and probenecid are sometimes given together to treat sexually transmitted diseases when a high semm level and prolonged level of cephalosporins are desirable. [Pg.241]

Pascale LR, Dubin A, Hoffman WS. Therapeutic value of probenecid (Benemid ) in gout... [Pg.138]

See other pages where Benemide - Probenecid is mentioned: [Pg.1678]    [Pg.1678]    [Pg.353]    [Pg.354]    [Pg.46]    [Pg.1678]    [Pg.1678]    [Pg.1678]    [Pg.1678]    [Pg.1678]    [Pg.1678]    [Pg.353]    [Pg.354]    [Pg.46]    [Pg.1678]    [Pg.1678]    [Pg.1678]    [Pg.1678]    [Pg.189]    [Pg.21]    [Pg.52]    [Pg.51]    [Pg.276]    [Pg.70]    [Pg.138]    [Pg.148]    [Pg.345]    [Pg.1230]    [Pg.538]    [Pg.84]   


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Benemid

Benemid - Probenecid

Benemid - Probenecid

Probenecid

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