Beneficial Role of Inflammation in Parkinsons Disease

Several in vivo stuckes support the capacity of inflammation in mecUating neuroprotective and neurodegenerative properties in the nervous system. One such example is the facial nerve axotomy paracUgm in newborn rats and rabbits. In this system model, axotomized motor neurons recover coincidentally with the development of the glial response (Moran and Graeber, 2004). It was also shown that a month after implantation of 

Among the range of reacdve species produced by glial cells, significant attendon has been given to RNS due to the 

PD is a common neurodegeneradve disorder characterized by motor abnormal des and a loss of primarily but not exclusively dopaminergic neurons. Other neuropathological hallmarks of PD include the proteinaceous inclusion, Lew y body and various inflammatory changes. The inflammation is made up of resident innate and to lesser extent adapdve immune cells. Similar inflammatory changes are found in both sporadic and familial non-PD parkinsonian syndromes and in experimental models 

What is the difference between parkinsonian syndrome and Parkinson s disease  

Wliat ai e the sunilaidties and differences in theinflamma-tory response among PD, the various parkinsonian syndromes, and die common expeiimental models of PD  

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