Beech synthesis

BORSCHE - BEECH Aromatic Aldehyde Synthesis Synthesis of aromatic aldehydes and of akyl aryl ketones from aldoximes or semcaibazones and aromatic dlazonum salts... 

Francke W., Schroder F., Kohnle U. and Simon M. (1996a) Synthesis of (lS,2R,5R)-2-ethyl-l,5-dimethyl-6,8-dioxabicyclo [3.2.1] octane, the aggregation pheromone of male beech bark beetle, Taphrorychus bicolor (Col., Scol.). Liebigs Ann. 10, 1523-1527. 

Kusel K. and Drake H. L. (1994) Acetate synthesis in soil from a Bavarian beech forest. Appl. Environ. Microbiol. 60, 1370-1373. 

The first, path (1), was straightforward since all N-aminohet-erocycles used in this work (Table V) were known, and methods for their preparation have been published. The majority of the sub-stituted-benzaldehydes used in this method were prepared according to the Beech (17) method as described (18) for the conversion of 2-bromo-4-toluidine into 2-bromo-4-methylbenzaldehyde. The method is of wide application and gave substituted benzaldehydes in 50-75% yield. The unavailability of certain (polyfluoroalkoxy)anilines precluded synthesis of corresponding aldehydes via this method. These were prepared from anisic acids (Chart III) or reduction of nitro-phenols. For example, conversion of meta-anisic acid into 3-(tri-... 

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