Batch Injection Analysis Principles

In search of both sensitivity and practicability of the assay, the reaction pathway and the particular mechanism of inhibition may preliminarily determine the particular detection principle. Without exception, most common detection techniques have been implemented with this biorecognition principle, employing varied assay formats using either batch mode or any modality of flow injection analysis. 

Flow injection analysis (FIA) was first introduced by Ruzicka and Hansen in 1975. FIA is a technique for the manipulation of the sample and reagent streams in instrumental analysis. The purpose of flow injection is to have sample preparation and injection take place automatically in a closed system. The flow injection technique combines the principles of flow and batch type processing and it consists of a set of components which can be used in various combinations. 

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