Barrett, Michael

Mason, Lee and Barrett, Michael. Preliminary Comments on Potential Brayton Turboalternator Failure Modes. Feb. 14, 2005... 

Michael G. Barrett Kenneth O. MacFadden Jean A. Taylor... 

Michael R. Barrett United States Environmental Protection Agency, Washington, DC, USA... 

Barrett and coworkers have explored hetero-substituted nitroalkenes in organic synthesis. The Michael addition of nucleophiles to 1-alkoxynitroalkenes or 1-phenylthionitroalkenes followed by oxidative Nef reaction (Section 6.1) using ozone gives a-substituted esters or thiol esters, respectively.41 As an alternative to nucleophilic addition to l-(phenylthio)-nitroalkenes, Jackson and coworkers have used the reaction of nucleophiles with the corresponding epoxides (Scheme 4.4).42 Because the requisite nitroalkenes are readily prepared by the Henry reaction (Chapter 3) of aldehydes with phenylthionitromethane, this process provides a convenient tool for the conversion of aldehydes into ot-substituted esters or thiol esters. 

It is interesting to note that the oxa-analogous Michael addition was reported for the first time in 1878 by Loydl et al. [19] in their work on the synthesis of artificial malic acid, which was five years ahead of the discovery of the actual Michael reaction described first by Komnenos [20], Claisen [21], and later Michael in 1887 [22] as one of the most important methods for C—C bond formation. In continuation of the early work on the oxa-Michael addition [23], the inter- and intramolecular additions of alkoxides to enantiopure Michael acceptors has been investigated, leading to the diastereo- and enantioselective synthesis of the corresponding Michael adducts [24]. The intramolecular reaction has often been used as a key step in natural product synthesis, for example as by Nicolaou et al. in the synthesis of Brevetoxin B in 1989 [25]. The addition of oxygen nucleophiles to nitro-alkenes was described by Barrett et al. [26], Kamimura et al. [27], and Brade and Vasella [28]. 

Professor Bruce C Gilbert (Chair), university tf rot, uk Professor David W Aden, SkeffieMHafom Unrvmxy, UK Dr Graham Barrett O ont uk Dr George Davidson, Unrmnity of Nottingham uk Or John Davies University of Wak Swansea. IV Dr Michael Davies, ihe Hmt Research towns... 

Barrett, Amy, with Arndt, Michael, No Quick Cure, BusinessWeek, May 6, 2002. 

Thomas A. Shannon, director of the National School Boards Association, is pushing for a 12-month academic year. No summer idleness, either for students or school buildings. In Massachusetts, Michael Barrett, a state senator, has introduced a bill to extend the school year from 180 to 220 days. 

Maleimide is a well-known Michael acceptor, dienophile and dipolarophile and hence is another versatile functional moiety that has found multiple uses in combinatorial chemistry as both a scavenger as well as a template in library synthesis [15]. Barrett [16] and Porco [17] have both reported the synthesis of a polystyrene resin-supported maleimide but did not report its use in the scavenging of nucleophiles. Hall and coworkers have described the synthesis of a supported-maleimide... 

Targeting of Toxic Compounds to the Trypanosome s Interior Michael P. Barrett and Ian H. Gilbert... 

BARRETT 1801 confuses this sigil with that for the Archangel MICHAEL SCHETBLE 1848 gives several other variants,... 

Professor Bruce C Gilbert (Chair). University York. UK Professor David W Allen Sheffield Hallam Umvenity, UK Dr Graham Barrett Ojff>rJohn Davies University Wales. Swansea. UK Dr Michael Davies, The Heart Researcn Insotute. 

In his research, the author has benefited from consultation and collaboration with numerous individuals including, most prominently, Terrence Green, Seymour J. Klebanoff, and Henry Rosen, and in his own laboratory, J. Michael Albrich, William C. Barrette, Jr., and Diane Hannum. His work is supported by Public Health Service Grant AI-15834 from the National Institute of Allergy and Infectious Diseases. 

The most recent entry to bicyclic P-lactam compounds through this approach, has been introduced by Barrett and his coworkers [120] by using an intramolecular Michael type reaction of a Af-silyl p-lactam to a nitroalkene induced by fluoride ion (Scheme 45). Namely, the known P-lactam 299 [32a] readily prepared from CSI addition to 1,5-hexadiene, was protected by using TBDMSCI and DIPEA to produce the p-lactam 300. Subsequent ozonolysis, gave the aldehyde 301. Henry reaction of the aldehyde 301 with (phenylthio)-nitromethane furnished, after dehydration of the resulting nitroaldol, the nitroalkene 302 which smoothly cyclized to the carbapenam 303 in the presence of... 

Carter, Michael R., and Christopher B. Barrett. 2006. The Economics of Poverty Traps and Persistent Poverty An Asset-Based Approach. Journal of Development Studies 42 (2) 178—99. 

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