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Barbiturates therapeutic risks

BARBITURATES PROCARBAZINE t risk of hypersensitivity reactions in patients with brain tumours Strong correlation between therapeutic antiepileptic level and hypersensitivity reactions Consider using non-enzyme-inducing agents... [Pg.212]

BARBITURATES FLUCONAZOLE, ITRACONAZOLE, KETOCONAZOLE, VORICONAZOLE 1 azole levels with risk of therapeutic failure Barbiturates induce CYP3A4, which metabolizes itraconazole and the active metabolite of itraconazole. Primidone is metabolized to phenobarbitone Watch for inadequate therapeutic effects and t dose of azole if effect due to interaction... [Pg.213]

CICLOSPORIN ANTI EPILEPTICS -BARBITURATES, CARBAMAZEPINE, PHENYTOIN L plasma concentrations of ciclosporin, with risk of transplant rejection Due to induction of metabolism of ciclosporin by these drugs. The potency of induction varies Monitor for signs of rejection of transplants. Monitor ciclosporin levels to ensure adequate therapeutic concentrations and t dose when necessary... [Pg.361]

TEUTHROMYCIN BARBITURATES 1 levels of these drugs, with risk of therapeutic failure Induction of hepatic metabolism 1. Avoid co-administration of telithromycin for up to 2 weeks after stopping phenobarbital 2. With the other drugs, monitor for l clinical efficacy and T dose as required... [Pg.519]

I levels of these drugs with risk of therapeutic failure. The I anticoagulant effect of warfarin reaches a maximum after 3 weeks and can last up to 6 weeks after stopping barbiturates... [Pg.288]

The concurrent use of small or moderate amounts of alcohol and therapeutic doses of drugs that are CNS depressants can increase drowsiness and reduce alertness. These drugs include antidepressants, antiemetics, antiepileptics, antihistamines, antipsychotics, anxiolytics, barbiturates, hypnotics, opioid analgesics, skeletal muscle relaxants, and others. This increases the risk of accident when driving or handling other potentially dangerous machinery, and may make the performance of everyday tasks more difficult and hazardous. [Pg.59]

See other pages where Barbiturates therapeutic risks is mentioned: [Pg.144]    [Pg.138]    [Pg.319]    [Pg.7]    [Pg.138]    [Pg.300]    [Pg.319]    [Pg.38]    [Pg.211]    [Pg.103]    [Pg.492]    [Pg.467]    [Pg.277]    [Pg.144]    [Pg.138]    [Pg.300]    [Pg.990]   
See also in sourсe #XX -- [ Pg.685 ]



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