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Nortriptyline Barbiturates

Additive effects are likely after concomitant use of nortriptyline with CNS depressants, including alcohol, analgesics, barbiturates, narcotics, tranquilizers, and anesthetics (oversedation) atropine and other anticholinergic drugs, including phenothiazines, antihistamines, meperidine, and antiparkinsonian agents (oversedation, paralytic ileus, visual changes, and severe constipation) and metrizamide (increased risk of convulsions). [Pg.507]

Barbiturates and heavy smoking induce nortriptyline metabolism and decrease therapeutic efficacy phenothiazines and haloperidol decrease its metabolism, decreasing therapeutic efficacy methylphenidate, cimetidine, oral contraceptives, propoxyphene, and beta-blockers may inhibit nortriptyline metabolism, increasing plasma levels and toxicity (see Tables 5 through 7). [Pg.507]

Simultaneous alimemazine, amitriptyline, amphetamine, bupivacaine, buprenorphine, clomipramine, cocaine, codeine, ethylmorphine, glafenine, meperidine, methampheta-mine, methotrimeprazine, morphine, norcodeine, nortriptyline, pentazocine Noninterfering acetaminophen, aspirin, barbiturates, benzoylecgonine, caffeine, diazepam, flunitrazepam, lidocaine, lorazepam, nalorphine, naloxone, nitrazepam, nordiaze-pam, norflunitrazepam, normorphine, oxazepam, prazepam, triazolam, zolpidem Interfering cyamemazine, desipramine, imipramine... [Pg.1192]

The plasma levels of amitriptyline, imipramine and nortriptyline can be reduced by the barbiturates. A reduced therapeutic response would be expected. The tricyclics also lower the convulsive threshold and may be inappropriate for patients with convulsive disorders. [Pg.1231]

A comparative study in 5 pairs of twins given nortriptyline found that the twins also taking unnamed barbiturates had considerably lower steady-state plasma nortriptyline levels. ... [Pg.1231]


See other pages where Nortriptyline Barbiturates is mentioned: [Pg.245]    [Pg.245]    [Pg.246]    [Pg.245]    [Pg.72]    [Pg.395]    [Pg.314]    [Pg.245]    [Pg.395]   
See also in sourсe #XX -- [ Pg.1231 ]




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Barbiturics

Nortriptyline

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