Barbatosides

A current compilation of Mexican medicinal plants indicates that no pharmacological studies have been carried out to test the presumed properties of the decoction [13]. Chemical studies of the aerial parts of Penstemon barbatus have afforded four aucubin iridoid glycosides catalpol (53), scutellarioside (54), globularin (55) and barbatoside (56) "Fig. (15)." The two former compounds were isolated as their acetate derivatives [101]. Several iridoid glycosides have shown anti-inflammatory activity in experimentally induced edema in mice best results were obtained when administered topically. The most active compounds were two catalpol derivatives, besides aucubine, verbalin and loganin these compounds induced a 72 to 80% edema inhibition when applied at a dose of 1 mg/ear [102]. 

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