Bar gene

Barex 210 resin, l 450t Barex 218 resin, l 450t Barex resins, 1 449-452 properties of, l 450t BArF anions, 16 95 bar gene, 13 360, 36 It Barge transport, 25 327 Barite, 3 343, 351, 352-355 17 691... 

Figure 36-4. Illustration of the tight correlation between the presence of RNA polymerase II and RNA synthesis. A number of genes are activated when Chirono-mus tentans larvae are subjected to heat shock (39 °C for 30 minutes). A Distribution of RNA polymerase II (also called type B) in isolated chromosome IV from the salivary gland (at arrows). The enzyme was detected by immunofluorescence using an antibody directed against the polymerase. The 5C and BR3 are specific bands of chromosome IV, and the arrows indicate puffs. B Autoradiogram of a chromosome IV that was incubated in H-uridine to label the RNA. Note the correspondence of the immunofluorescence and presence of the radioactive RNA (black dots). Bar = 7 pm. (Reproduced, with permission, from Sass H RNA polymerase B in polytene chromosomes. Cell 1982 28 274. Copyright 1982 by the Massachusetts Institute of Technology.)...

Fig. 4.3 Epidermal nerve fiber illustrated in a 50-pm vertical skin section, immunostained with the panaxonal marker anti-protein gene product 9.5. Skin section showing epidermal nerve fiber density arrows) in the distal leg of a healthy adult (a) and reduced epidermal nerve fiber density and degenerating fibers arrows) in the distal leg of a HIV-associated sensory neuropathy patient (b) (scale bar, 50 pm). Courtesy of Drs Gigi Ebenezer and Justin McArthur, Johns Hopkins University, Baltimore, Maryland, USA...

Figure 1. The detailed restriction map of the 3.0 kb EcdFl fragment of the XE6 clone. The position of pgaE gene is shown by the black bar. This fragment was cloned into pBluescript SK and further analysed.

Fig. 3. Model for the two-dimensional arrangement of the human erythrocyte glucose transporter in the membrane. Amino acid residues are identified by their single letter code. Solid bars indicate the location of introns in the transporter gene. The regions coloured black are released from the membrane upon tryptic digestion. Shaded segments indicate the probable regions photolabelled by ATB-BMPA (helix 8) and by cytochalasin B (helix 11 and the loop connecting it to helix 10). The circles with heavy outlines indicate the region labelled by lAPS-forskolin (helix 10).

Figure 5. Tyrosinase gene expression in melanocytes of the hair follicle. Bright field photographs show sections of skin of 4-day-old albino mice. Bar represents 50 pm.

Figure 6. Transgene and tyrosinase gene expression in early eye development. Sections are derived from embryonic day 10.5 (A, B), 12.5 (C, D), 13.5 (E), and 17.5 (F) (for details see Beermann etal., 1992a,b). Transgene-specific expression (ptrTyrS) is depicted in A, B, E, F, and tyrosinase gene expression in C and D. In A-D, the same section was photographed both in dark field (A, C) and in bright field (B, D). Bar represents 150 pm in A, B 250 pm in C, D, E and 200 pm in F.

Figure 4.2 Hypothetical plasma membrane (PM)-associated structure of FR02. Four histidine residues (white spots) predicted to coordinate two intramembraneous haem groups (white bars) are indicated, as are the tetrapeptide binding sites for FAD and N AD(P)H. The sites of mutations in the FRO gene are indicated (frdl-l,frdl-3) i, inside cell o, outside cell. Reprinted with permission from Nature (Robinson et al., 1999). Copyright (1999) Macmillan Magazines Limited.

Fig. 15.4 Diagram showing the main pharma cokinetic and pharmacodynamic events mediated by the gene-protein network within the endothelial cells (EC), pericytes (P) and astrocytes (A). The intracellular cross-talk pathways that modulate the blood-brain bar-...

Figure 1. The frequencies of amber mutations in the lacl gene induced by BPDE. Solid bars, individual sites at which we detected mutations open bars, sites at which we did not detect mutations asterisks (in a), sites at which the target codon contains 5-methylcytosine.

Figure 18.17 Frataxin mutations. The commonest mutation is the GAA expansion in the first intron of the frataxin gene (98%). Boxes represent exons and blue bars introns of the frataxin gene. Asterisks indicate the number of families reported with each mutation. From Durr, 2002. Copyright 2003, with permission from Elsevier.

CNTs can also be encapsulated with DNA molecules. As shown in Fig. 9.1, a DNA molecule could be spontaneously inserted into a SWNT in a water solution via molecular dynamics simulation (Gao et al., 2003). The van der Waals and hydrophobic forces were very key factors for the insertion process, with the former playing a more dominant role in the course of DNA entering into the hole of CNT. Experiment also confirmed that Pt-labeled DNA molecules can be encapsulated into multi-walled carbon nanotubes in water solution at 400 K and 3 Bar as shown in Fig. 9.2 (Cui et al., 2004). The CNTs filled with DNA molecules have potential in applications such as gene delivery system, and electronic sequencing, nanomotor, etc. 

Figure 6. Comparative gene expression ratios in ARF kidneys of MSC- and vehicle-treated animals. Data were generated by referencing each gene to p-actin as internal control. A MSC treatment cansed significant (P < 0.05) suppression (> 10 fold) of proinflammatory IL-ip, TNF a, and IFN-y (above bars actnal valnes). Anti-inflammatory lL-10 was robustly expressed in MSC-and not in vehicle treated animals. Filled bars on all panels depict gene expression ratio of 1, i.e., a value obtained when gene expression ratios between MSC- and vehicle-treated animals are "equal. B MSC treatment cansed increased gene expression of bFGF and TGF-a, whereas that of HGF was suppressed. C antiapoptotic Bcl-2 expression was robnstly indnced, whereas that of inducible nitric oxide synthase (iNOS) was snppressed in MSC- vs. vehicle-treated animals. eNOS, endothelial NOS.

HMGA Binding Sites on Promoter/Enhancer Regions form a Gene-Specific Bar Code ... 

---