Balkan nephropathy chromosomes

Currently one research group argues in favor of a crucial role of genetic factors. They identified a specific chromosome marker (3q25) in Balkan nephropathy patients [24-26]. Another research team saw some aberrations of the X chromosome, but they resembled changes occurring after exposure to ocharatoxin A [27]. 

Toncheva D, GergovT, Tzoneva M, BouchakllevZ. Spontaneous and Induced chromosome aberrations In Balkan endemic nephropathy. Kidney Int. 1991 40 (SuppI. 34) 97-101. 

Manolova Y, Manolov G, Parvanova L, Petkova-Bocharova T, Castegnaro M, Chernozemsky IN. Induction of characteristic chromosomal aberrations, particularly X-trisomy, in cultured human lymphocytes treated by ochratoxin A, a mycotoxin implicated in Balkan endemic nephropathy. Mutat. Res. 1990 231 (2) 143-9. 

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