Balancing Thoroughness vs Time and Resources

Some important parameters that must be taken into account in balancing the degree of analytical thoroughness vs available time and resources (financial and 

From a practical perspective, several key factors wiU need to be considered in order to determine how much time should be invested in the development of the method. Assuming that the method criteria and reporting requirements are the same, the number of samples to be analyzed will have a direct impact on the method objectives and 

The compromise between a higher precision (and thus higher cost) analytical method and lower financial risk can sometimes be significantly shifted by improving the quality of the chemical analysis (using the same optimum method) as it is actually performed in the laboratory. This can potentially be achieved by using standardized methods 

at this stage, the analyst feels that it is not possible to perform the analyses of the quality required to meet the customer s purpose within the latter s budget and/or within the time available, it is always best to be frank with the customer about the dilemma and help him/her to decide what to do about the situation. Any compromises that could lead to increased uncertainty in the method should be documented prior to sample analysis, along with how results will be reported in general. If an agreement (documented ) is reached to proceed, development of the analytical method in accord with the agreed analytical purpose can begin. 

---