Baccharis tricuneata

Clerodanes.—In a study of South African Macowania species, a cis-clerodane acid (28) and labdanolic acid were obtained from M. glandulosa. Deoxymarrubialac-tone (29) has been isolated from Chaiturus marrubiastrum. Linarienone (30) is another ds-fused clerodane which has been obtained from the roots of Linaria japonica (Scrophulariaceae) and correlated with linaridial. The bacchotricuneatins A (31) and B (32) are two new diterpenoid lactones which were isolated from Baccharis tricuneata (Astereae) and whose structures were determined by a combination of spectra and X-ray analysis. 

Baccharis jloribunda H.B.K. ( Niquitao ) and Baccharis tricuneata (L.f.) Pers. ( Sanalotodo ) are used in Venezuela as decoctions or infusions of leaves and stems for skin infections and diabetes [14,15]. 

Constit. of Baccharis tricuneata. Cryst. (CH2Cl2/hexane). 

Wagner, H., R. Seitz, V.M. Chari, and H. Lotter Bacchotrcuneatin A and B, zwei neue diterpenlactone aus Baccharis tricuneata var. trie. Tetrahedron Lett. 1977, 3039. 

This diterpene lactone, bacchotricuneatin A was also isolated from B. tricuneata [24] and Baccharis cassinaefolia D. C. [25],... 

A number of these compounds have insect antifeedant activity. The total synthesis of the substituted c/s-decalin (26) as an antifeedant has been reported. Clerodanes have previously been detected in Salvia (Labiatae) species. The gesnerohlins A and B, obtained from S. gesneraefolia, have been assigned the structures (27) and (28) although their absolute stereochemistry was not determined. A further series of clerodanes of uncertain stereochemistry has been isolated from Baccharis species, including bacrispine (29) from B. crispa and the malonate ester (30) from B. tricuneata. ... 

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