Autonomic drugs acting at cholinergic synapses

Muscarinic agimisis (lop left) have few uses, but pilucarpine (as eyedrops) is used to reduce intraoeukir pressure in patient.s with giaucoma (Chapter id). Carbachol and bethanechol are used to 

Anticholinesterases (bottom left) have relatively little effet-i at ganglia and lue used mainly for their nicotinic effects on Lite neuromuscular junction. Tliey ate used in the treaimenl of myasthenia gravis and 10 reverse Ihe effects of competitive muscle rclaxanLs used during surgery (ChapterbJ. 

1 in anaesthesia to block vagal slowing of the heart and to inhibit bronchial secretion  

2 to reduce intestinal spasm in. for example, irritable bowel syndrome (Chapter 13)  

5 to dilate the pupil forophthalmological examination (e.g. tropicamide) or to paralyse the ciliary muscle (Chapter 10) and 

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