Aureus database

AurSCOPE databases. Aureus Pharma, Paris, France. http //www.aureus-pharma. com. 

AurSCOPE Databases containing biological and chemical information relating to a class of drug targets or a pharmaceutical topic of interest http //www.aureus-pharma.com/... 

Harmsen, D., Claus, H Witte, W Rothganger, J Claus, H., Turnwald, D., and Vogel, U. (2003) Typing of methicillin-resistant Staphylococcus aureus in a university hospital setting by using novel software for spa repeat determination and database management. J. Clin. Microbiol. 41, 5442-5448. 

Lasch and cowoikers describe in Chap. 8 their group s efforts to improve taxonomic resolution without compromising the simplicity and the speed of MALDI TOF MS. Such improvements may be achieved by signature database expansion with novel and diverse strains, optimization, and standardization of sample preparation and data-acquisition protocols. Further enhancement in data analysis pipelines including more advanced spectral preprocessing, feature selection, and supervised methods of multivariate classification analysis also contribute to taxonomic resolution enhancements. Strains of Staphylococcus aureus. Enterococcus faecium, and Bacillus cereus are selected to illustrate aspects of that strategy. 

Szabados F, Woloszyn J, Richter C, Kaase M, Gatermann S. Identification of molecularly defined Staphylococcus aureus strains using matrix-assisted laser desorption/ionization time of flight mass speetrometry and the Biotyper 2.0 database. J Med Microbiol. 2010 59 787-90. 

The MICs have been calculated for all peptides active against S. aureus present in the database. We calculated the precision (PPV), the accuracy (ACC), the sensitivity (TPR)and the specificity (SPC) as defined in Eqs. 3-6. 

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