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Atypical/Nor98 scrapie

Keywords Animal Atypical Atypical/Nor98 scrapie BSE-H BSE-L Human Prion disease Prion strain Prion type... [Pg.24]

Fig. 1 Comparison of classical scrapie and atypical/Nor98 scrapie with regard to overall distribution of PrPSc in the brain (drawings a,d), immunohistochemical PrPSo staining patterns in the cerebellum (b,e) and PrPSo banding pattern as revealed in Western Blots (c,f)... Fig. 1 Comparison of classical scrapie and atypical/Nor98 scrapie with regard to overall distribution of PrPSc in the brain (drawings a,d), immunohistochemical PrPSo staining patterns in the cerebellum (b,e) and PrPSo banding pattern as revealed in Western Blots (c,f)...
In addition to the difference in lesion profile, the pattern of PrPSc deposits in such atypical scrapie cases also differs from that seen in classical scrapie cases [109, 122], In classical scrapie, a stellate pattern of PrPSc deposits is particularly prominent in the granular layer of the cerebellum, while in atypical/Nor98 scrapie a widespread, diffuse, synaptic type of staining can be observed in the molecular or the granular cell layers or both, and may be variably associated with globular staining in the white matter. [Pg.33]

PrP allelic association with occurrence of classical scrapie and atypical/Nor98 scrapie... [Pg.35]

Fig. 2 Cartoon of PrP allelic association with occurrence of classical scrapie and atypical/Nor98 scrapie. While classical scrapie occurs most frequently in sheep with VRQ and ARQ alleles, atypical/Nor98 scrapie occurs most frequently in AFRQ and AHQ PrP alleles. The presence of the ARR allele confers strong resistance towards classical scrapie, while this is not the case for atypical/Nor98 scrapie... Fig. 2 Cartoon of PrP allelic association with occurrence of classical scrapie and atypical/Nor98 scrapie. While classical scrapie occurs most frequently in sheep with VRQ and ARQ alleles, atypical/Nor98 scrapie occurs most frequently in AFRQ and AHQ PrP alleles. The presence of the ARR allele confers strong resistance towards classical scrapie, while this is not the case for atypical/Nor98 scrapie...
Ministry of Agriculture and Forestry (MAF) and New Zealand Food Safety Authority (2009) Atypical/Nor98 scrapie in New Zealand, http //www.biosecurity.govt.nz/media/28-10-09/ atypical-scrapic-dctcction... [Pg.48]

See other pages where Atypical/Nor98 scrapie is mentioned: [Pg.23]    [Pg.24]    [Pg.26]    [Pg.26]    [Pg.31]    [Pg.32]    [Pg.32]    [Pg.32]    [Pg.33]    [Pg.33]    [Pg.33]    [Pg.34]    [Pg.34]    [Pg.35]    [Pg.35]    [Pg.35]    [Pg.36]    [Pg.23]    [Pg.24]    [Pg.26]    [Pg.26]    [Pg.31]    [Pg.32]    [Pg.32]    [Pg.32]    [Pg.33]    [Pg.33]    [Pg.33]    [Pg.34]    [Pg.34]    [Pg.35]    [Pg.35]    [Pg.35]    [Pg.36]    [Pg.34]    [Pg.83]    [Pg.227]   
See also in sourсe #XX -- [ Pg.23 ]



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