Athrombin - Warfarin sodium

The coumarin anticoagulants include dicumarol, warfarin sodium (coumadin sodium), warfarin potassium (Athrombin-K), acenocoumarol (Sintrom), and phenprocoumon (Liquamar). The inanedione derivatives are phenindione (Hedulin), diphenadione (Dipaxin), and anisindi-... 

The coumarin anticoagulants include dicumarol, warfarin sodium (coumadin sodium), warfarin potassium (Athrombin-K), acenocoumarol, and phenprocouman. Phenprocouman, acenocoumarol, and ethyl biscoumacetate are not generally available in the United States but are prescribed in Europe and elsewhere. Phenprocouman (Marcumar) has a longer plasma half-life (5 days) than warfarin, as well as a somewhat slower onset of action and a longer duration of action (7 to 14 days). It is administered in daily maintenance doses of 0.75 to 6.0 mg. By contrast, acenocoumarol (Nicoumar-lone Sinthrome) has a shorter half-life (10 to 24 hours), a more rapid effect on the prothrombin time, and a shorter duration of action (2 days). The maintenance dose is 1 to 8 mg daily. Ethyl biscoumacetate (Tromexane) has a very short half-life of 2 to 3 hours and is seldom used. 

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