Asymmetric transfer hydrogenation of acetophenone

Table 41.15 Recycling of 9- and 10-Ru in the asymmetric transfer hydrogenation of acetophenone with the azeotrope in [BMIM][PF6] [110].

Scheme 6-51. Asymmetric transfer hydrogenation of acetophenone in the presence of 119. Reprinted with permission by Am. Chem. Soc., Ref. 112.

Ruthenium-catalysed asymmetric transfer hydrogenation of acetophenone 133... 

S. Laue, L. Greiner J. Woltinger, and A. Liese, Continuous application of chem-zymes in a membrane reactor asymmetric transfer hydrogenation of acetophenone, Adv. Synth. Catal. 2001, 343, 711-720. 

Dissymmetric ferrocenyldiphosphines have been synthesized from (R)-(+)-N, N -dimethylaminoethylferrocene. The diphosphines have been used as ligands in asymmetric transfer hydrogenation of acetophenone in the presence of ruthenium catalysts.297 Asymmetric transfer hydrogenation of a,/S-unsaturated aldehydes with Hantzsch dihydropyridines and a catalytic amount of MacMillan imidazolidinone salt (12) leads to the saturated carbonyl compounds in high yields and excellent chemo-and enantio-selectivities.298 ... 

A ruthenium complex containing a novel imidazolium salt moiety catalyses the asymmetric transfer hydrogenation of acetophenone derivatives, with a formic acid- triethylamine azeotropic mixture in an ionic liquid, [bmim][PF6]. The yields and ee are excellent.308... 

A method for the monoarylation of (15,25)-l,2-diaminocyclo-hexane by means of palladium-catalyzed aromatic amination has been recently described (eq 13). The resulting new ligands were tested in the catalytic asymmetric transfer hydrogenation of acetophenone. 

A chiral diaminodiphosphine ligand was attached onto poly(acrylic acid) through an amide linkage. The ruthenium(II) complex of the resultant polymeric ligand (169) was then applied to the asymmetric transfer hydrogenation of acetophenone in 2-propanol (Scheme 3.51) [101]. (S)-l-phenylethanol was obtained in 95% yield with 96% ee by using 158. 

Enantioselective Catalysis in Ionic Liquids 245 Table 7.6 Asymmetric transfer hydrogenation of acetophenone in ionic liquids. 

Scheme 6 Asymmetric transfer hydrogenation of acetophenone derivatives by Ru precatalysts (S,S)-9 and 10 with tetradentate ligands " ...

RuGl2(G6H6)]2 is an efficient, recyclable catalyst for the asymmetric transfer hydrogenation of acetophenone derivatives with a formic acid-triethylamine azeotropic mixture in [G4GiIm]PF6 (Figure... 

Sun, X. Manos, G. Blacker, J. Martin, J. Gavriilidis, A. Asymmetric transfer hydrogenation of acetophenone with lR,2S-aminoindanol/pentamethylcy-clopentadienylrhodium Catalyst. Org. Process Res. Dev. 2004,8,909-914. 

Table 6.7 Asymmetric transfer hydrogenation of acetophenone using ligand 41-43...

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