Astrocytes calcium microdomains

Localized Calcium Microdomains Control Exocytosis of Glutamate in Astrocytes... 

Adherent cells have also been patterned using cell-adhesive and non-cell-adhesive microdomains created on a glass coverslip. This coverslip was then bonded with a PDMS channel layer for cell patterning [857]. For instance, endothelia or astrocyte-neuron cocultures were plated only on the cell-adhesive poly-L-lysine microdomains, but not on the non-adhesive agarose (1%) microdomains. Subsequently, calcium wave measurements were made to study calcium signaling of cells in two modes (1) within confluent cell microdomains, and (2) across neighboring, but spatially disconnected, microdomains [857]. 

---