Aspergillus cell factories

Characteristics and Applications of Aspergillus Species as Cell Factories. 76... 

There is substantial industrial interest in the exploitation of Aspergillus species as cell factories. Therefore it is obvious to consider the exploitation of the solid knowledge base from systems biology for future design of improved and better cell factories. A major hurdle in this exploitation is that many of the high-through-put experimental techniques and bioinformatics tools available for analysis of the datasets are not well suited for fungi, at least not as well as for S. cerevisiae. 

Papagianni M, Mattey M. Morphological development of Aspergillus niger in submerged citric acid fermentation as a function of the spore inoculum level. Application of neural network and cluster analysis for characterization of mycelial morphology. Microb Cell Factories 2006 5 3. 

Pel HJ, de Winde JH, Archer DB, et al. Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88. Afar Biotechnol 2007 25 221-31. 

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